Some things are not interchangeable. It is impossible for men to give birth, labor and delivery belongs only with the glory of women. Other exchanges are necessary; our deliverance from sin’s penalty and power depend on it.
Therefore He had to be made like His brothers in every respect, so that He might become a merciful high priest in the service of God, to make propitiation for the sins of the people. (Hebrews 2:17)
He who knew no sin became sin, the sinless exchanged Himself for the sinful. He who was strong died in place of the weak. The righteous took on our unrighteousness and made it so that the unrighteous might share His righteousness. The immortal took on mortality, and then died in order to destroy death.
The gospel is a great exchange. His sacrifice in our place is the purchase of salvation. He died the death we deserved that we might live in His life.
For salvation there is neither male nor female, all are welcome in fellowship with the Father by faith alone in Jesus Christ His Son.